$600-$850 billion healthcare system waste per annum--Unflappable Sen. Tom Coburn 'unflappably' used Thomson Reuters' "Where Can $700 Billion In Waste Be Cut Annually From the U.S. Healthcare System?" [10/2009] as an authoritative reference; it names the most significant drivers of wasteful healthcare system spending: Unwarranted Use: $250-$325 billion   Fraud and Abuse: $125-$175 billion Lack of Care Coordination: $25-$50 billion Administrative System Inefficiencies: $100-$150 billion